The overall aim of this symposium is to seek new opportunities for the replacement of mammalian models by drawing together the long standing expertise of the comparative physiologists who pioneered and developed in vitro systems in non-mammalian species, and to share this expertise with the toxicology community including mammalian toxicologists, ecotoxicologists, policy makers and regulators, who are increasingly interested in the role of alternative models in hazard assessment. This meeting is organised by popular demand, following a session held on in vitro techniques at the Society for Experimental Biology (SEB) annual meeting in 2007. The symposium in 2009 will gather the most up-to-date information on in vitro techniques with fish and invertebrates, and explore the applications of this work in fundamental toxicology research and the regulatory arena.

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